Research

Our Department has a long and successful track record with clinical research.  Our faculty are involved in an excellent mix of investigator initiated studies, collaboration with other academic medical centers in multicenter studies, and pharma/industry sponsored research.

Residents are taught the basics of research methodology during their training.  Every resident is expected to complete a research study and submit it for publication (although publication is not a requirement).  Residents present their research at our Annual Resident Research Day; in June 2010, we celebrated our 18th Annual Resident Research Day.  Residents may work together or alone on a study; all projects however, have a faculty mentor to assist the resident and guide them successfully through the various processes (ie, Institutional Review Board approval; statistical analysis, etc.) involved in research.

Residents are encouraged to submit their research for presentation at the SAEM Annual Meeting and/or the ACEP Research Forum.  For the last ten years, residents and faculty have presented their research at these national forums.  For residents, all of the costs associated with presenting (ie, air travel, lodging, meals, etc.) are paid for by the department.  Residents have also been successful in seeing their research through to publication, with nearly half being published in the peer-reviewed literature.

Areas of faculty research interest and expertise include:  ultrasound; respiratory emergencies; educational and translational research; airway management; EBM; emergency medical services; use of biomarkers; and wound management.  Our residents and faculty have been recognized for their outstanding research on multiple occasions by the Virginia College of Emergency Physicians (VACEP).  Each year, VACEP presents the “John P. McDade Award for Outstanding Research in Emergency Medical Care” – one for residents and one for faculty.  Emergency Medicine residency programs from the University of Virginia, the Virginia Commonwealth University and Naval Medical Center Portsmouth compete for this prestigious award.  Our residents have received this award more than any other EM residency program in Virginia. 

SELECTED STUDIES IN PROGRESS:
 
1. POINT Trial (Platelet-Oriented Inhibition in New TIA). A randomized, double-blind controlled trial evaluating if clopidogreal is effective in improving survival from major ischemic vascular events at 90 days for new TIAs or minor strokes.
Sponsor: NIH
Faculty: Bruce Lo, M.D., RDMS, FACEP

2. Human Papilloma Virus (HPV) testing in the Emergency Department
Faculty:  Alicia Devine, M.D., FACEP
Residents:  Valerie Baur, M.D., Reina Parker, M.D.
Received a $50,000 grant from Merck to conduct the study. 

3. B-RIPPED Ultrasound Study.  The use of ultrasound in evaluating patients presenting with dyspnea, examining for Right ventricle enlargement, IVC collapse, Pericardial effusion, Pleural effusion, PE and DVT.
Faculty: Don Byars, M.D, RDMS, FACEP, Barry Knapp, M.D., RDMS, FACEP, David Evans, M.D.
Residents:  Virginia Stewart, M.D., Valerie Baur, M.D., Brian Campbell, M.D.

4. The Role of a Structured Journal Club on Evidence Based Knowledge Acquisition in Postgraduate Emergency Medicine Education: Multi-Center Study.
Faculty : Charles Graffeo, MD., ABEM-UHM, Chris Carpenter, M.D. (Washington University), and B. Kane, M.D. (Lehigh Valley)

5. MN-221-CL007, A Phase II randomized, double-blind placebo controlled study to evaluate the safety and efficacy of MN-221 when administered intravenously as an adjunct to standard therapy to adults with an exacerbation of asthma.
Sponsor: MediciNova
Faculty:  Francis L. Counselman, M.D., CPE, FACEP

SELECTED RESEARCH PUBLICATIONS (faculty in bold, residents in italics):

1. Lo BM, Schott CK, Best HA, Visintainer CM: Utility of wet prep in predicting cervical infections in women (abstract). Ann Emerg Med 2010; 56(3):S32.
2. Devine AS, Jackson CS, Lyons L, Mason JD:  Frequency of incidental findings on computed tomography of trauma patients.  West J Emerg Med 2010; 11(1):24-27.
3. Byars D, Evans D, Lo B, Brodsky R, Walker L: Comparison of standard direct laryngoscopy versus pediatric King LT-D in a simulated difficult pediatric airway (abstract). Acad Emerg Med 2010; 17(5) Supp 1: S194.
4. Carpenter CR, Kane BG, Carter N, Lucas R, Wilbur LG, Graffeo CS: Incorporating evidence-based medicine into resident education: a CORD survey of faculty and resident expectations.  Acad Emerg Med 2010; 17:S54-S61.
5. Counselman FL, Marco CA, Patrick VC, et al:  A study of the workforce in emergency medicine: 2007. Am J Emerg Med 2009; 27(6):691-700.
6. Byars D, Tsuchitani S, Lo B, Dunn C, Fickenscher B, Walker L, Yeats J: Evaluation and retention of paramedic skills to properly utilize the I-LMA device in high fidelity simulated critical care scenarios (abstract). Acad Emerg Med 2010; 17(5): Suppl 1:S32.
7. Knapp B, Tsuchitani S, Watring N: Prevalence of Methicillin-resistant Staphylococcus aureus colonization on EMS providers (abstract).  Acad Emerg Med 2009; 16(4): Supp 1: S199.
8. Suzuki T, Distante A, Zizza A, Trimarchi S, Villani M, Uriarte JAS, Schinosa LDT, Renzulli A, Sabino F, Nowak R, Birhahn R, Hollander  JE, Counselman FL, et al.  Diagnosis of acute aortic dissection by D-dimer.  Circulation 2009; 119:2702-2707.
9. Knapp BJ, Kerns BL, Riley I, Powers J: EMS-initiated refusal of transport: the current state of affairs. J Emerg Med 2009; 36(2):156-161.
10. Graffeo C, Eastman J, McDonald J, Bossard S:  Screening for obstructive sleep apnea in emergency department patients: comparison of clinical pretest probability with a previous validated prediction tool (abstract). Acad Emerg Med 2007; 14(5) Suppl 1:S66-S67.
11. Knapp B, Sheele J: Prospective evaluation of a paramedic administrated EMS alternate transport protocol (abstract).  Acad Emerg Med 2007; 14(5):Suppl 1:S159.